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Toward the end from the rotation, the student will study several hottest procedures in mapping and analyzing next-technology sequencing information, and the way to examine transcriptome/methylome from the context of genetic polymorphisms.The aim is to delineate the methylome modifications and transcriptional consequences made by two developmental m

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We are interested during the interface of theoretical Laptop science and methods biology. By imagining computationally in regards to the aims, constraints, and algorithmic techniques employed by biological devices, we hope to advance both equally Pc science (by establishing new bio-impressed algorithms) and biology (by boosting testable hypotheses

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This project aims to utilize details produced from cells engineered to express a range of HNF1A mutations (MODY3 and non-MODY) accompanied by RNA-sequencing to discover a signature of genes that can distinguish among sulfonylurea responsive mutations and non-responsive mutations. This transcriptomic signature would form The premise of a biomarker c

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